Translocation of sickle cell erythrocyte microRNAs into Plasmodium falciparum inhibits parasite translation and contributes to malaria resistance

Erythrocytes carrying a variant hemoglobin allele (HbS), which causes sickle cell disease, resist infection by the malaria parasite Plasmodium falciparum. The molecular basis of this resistance, which has long been recognized as multifactorial, remains incompletely understood. Here we show that the...

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Bibliografiska uppgifter
Huvudupphovsmän: LaMonte, Gregory, Philip, Nisha, Reardon, Joseph, Lacsina, Joshua R., Majoros, William, Chapman, Lesley, Thornburg, Courtney D., Telen, Marilyn J., Ohler, Uwe, Nicchitta, Christopher V., Haystead, Timothy, Chi, Jen-Tsan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442262/
https://ncbi.nlm.nih.gov/pubmed/22901539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.06.007
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