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Population-based screening in the era of genomics

To date, risk profiles based on the known common susceptibility variants have limited value in predicting risk of disease but they could be used for risk stratification in prevention programmes at population level. We illustrate the potential utility of polygenic risk stratification using the case o...

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Autors principals: Pashayan, Nora, Pharoah, Paul
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442228/
https://ncbi.nlm.nih.gov/pubmed/22984365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pme.12.40
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