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Population-based screening in the era of genomics

To date, risk profiles based on the known common susceptibility variants have limited value in predicting risk of disease but they could be used for risk stratification in prevention programmes at population level. We illustrate the potential utility of polygenic risk stratification using the case o...

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Detalhes bibliográficos
Main Authors: Pashayan, Nora, Pharoah, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442228/
https://ncbi.nlm.nih.gov/pubmed/22984365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pme.12.40
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