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Gastro protective properties of the novel prostone SPI-8811 against acid-injured porcine mucosa
AIM: To evaluate the protective properties of novel prostone ClC-2 agonist SPI-8811 in porcine model of gastric acid injury. METHODS: Porcine gastric mucosa was mounted in Ussing chambers and injured by bathing mucosal tissues in an HCl Ringer’s solution (pH = 1.5) with or without SP1-8811 (1 μmol/L...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Baishideng Publishing Group Co., Limited
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442206/ https://ncbi.nlm.nih.gov/pubmed/23002337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i34.4684 |
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