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Gastro protective properties of the novel prostone SPI-8811 against acid-injured porcine mucosa

AIM: To evaluate the protective properties of novel prostone ClC-2 agonist SPI-8811 in porcine model of gastric acid injury. METHODS: Porcine gastric mucosa was mounted in Ussing chambers and injured by bathing mucosal tissues in an HCl Ringer’s solution (pH = 1.5) with or without SP1-8811 (1 μmol/L...

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Bibliografiske detaljer
Main Authors: Nighot, Meghali, Moeser, Adam, Ueno, Ryuji, Blikslager, Anthony
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Co., Limited 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442206/
https://ncbi.nlm.nih.gov/pubmed/23002337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i34.4684
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