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A synthetic prostone activates apical chloride channels in A6 epithelial cells

The bicyclic fatty acid lubiprostone (formerly known as SPI-0211) activates two types of anion channels in A6 cells. Both channel types are rarely, if ever, observed in untreated cells. The first channel type was activated at low concentrations of lubiprostone (<100 nM) in >80% of cell-attache...

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Detalhes bibliográficos
Main Authors: Bao, Hui Fang, Liu, Lian, Self, Julie, Duke, Billie Jeanne, Ueno, Ryuji, Eaton, Douglas C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519861/
https://ncbi.nlm.nih.gov/pubmed/18511742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00366.2007
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