Myodegeneration in EDA-A2 Transgenic Mice Is Prevented by XEDAR Deficiency

EDA-A1 and EDA-A2 are members of the tumor necrosis factor family of ligands. The products of alternative splicing of the ectodysplasin (EDA) gene, EDA-A1 and EDA-A2 differ by an insertion of two amino acids and bind to distinct receptors. The longer isoform, EDA-A1, binds to EDAR and plays an impor...

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Détails bibliographiques
Auteurs principaux: Newton, Kim, French, Dorothy M., Yan, Minhong, Frantz, Gretchen D., Dixit, Vishva M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
Sujets:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC344191/
https://ncbi.nlm.nih.gov/pubmed/14749376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.4.1608-1613.2004
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