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Tcra enhancer activation by inducible transcription factors downstream of pre-TCR signaling

The Tcra enhancer (Eα) is essential for pre-TCR-mediated activation of germline transcription and V(D)J recombination. Eα is considered an archetypical enhanceosome that acts through the functional synergy and cooperative binding of multiple transcription factors. Based on dimethylsulfate genomic fo...

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Bibliografiske detaljer
Main Authors: del Blanco, Beatriz, García-Mariscal, Alberto, Wiest, David L., Hernández-Munain, Cristina
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441836/
https://ncbi.nlm.nih.gov/pubmed/22357628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100271
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