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Tcra enhancer activation by inducible transcription factors downstream of pre-TCR signaling
The Tcra enhancer (Eα) is essential for pre-TCR-mediated activation of germline transcription and V(D)J recombination. Eα is considered an archetypical enhanceosome that acts through the functional synergy and cooperative binding of multiple transcription factors. Based on dimethylsulfate genomic fo...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3441836/ https://ncbi.nlm.nih.gov/pubmed/22357628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100271 |
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