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Interaction of C/EBP-beta and NF-Y factors constrains activity levels of the nutritionally controlled promoter IA expressing the acetyl-CoA carboxylase-alpha gene in cattle

BACKGROUND: The enzyme acetyl-CoA carboxylase-alpha (ACC-α) is rate limiting for de novo fatty acid synthesis. Among the four promoters expressing the bovine gene, promoter IA (PIA) is dominantly active in lipogenic tissues. This promoter is in principal repressed but activated under favorable nutri...

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Detalhes bibliográficos
Main Authors: Shi, Xuanming, Metges, Cornelia C, Seyfert, Hans-Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441787/
https://ncbi.nlm.nih.gov/pubmed/22738246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-13-21
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