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Imbalanced gp130-Dependent Signaling in Macrophages Alters Macrophage Colony-Stimulating Factor Responsiveness via Regulation of c-fms Expression

The mechanisms by which interleukin-6 (IL-6) family cytokines, which utilize the common receptor signaling subunit gp130, influence monocyte/macrophage development remain unclear. Here we have utilized macrophages devoid of either gp130-dependent STAT1/3 (gp130(ΔSTAT/ΔSTAT)) or extracellular signal-...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Jenkins, Brendan J., Grail, Dianne, Inglese, Melissa, Quilici, Cathy, Bozinovski, Steven, Wong, Peter, Ernst, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344172/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14749363/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.4.1453-1463.2004
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