Imbalanced gp130-Dependent Signaling in Macrophages Alters Macrophage Colony-Stimulating Factor Responsiveness via Regulation of c-fms Expression

The mechanisms by which interleukin-6 (IL-6) family cytokines, which utilize the common receptor signaling subunit gp130, influence monocyte/macrophage development remain unclear. Here we have utilized macrophages devoid of either gp130-dependent STAT1/3 (gp130(ΔSTAT/ΔSTAT)) or extracellular signal-...

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Hlavní autoři: Jenkins, Brendan J., Grail, Dianne, Inglese, Melissa, Quilici, Cathy, Bozinovski, Steven, Wong, Peter, Ernst, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC344172/
https://ncbi.nlm.nih.gov/pubmed/14749363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.4.1453-1463.2004
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