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Protein Kinase B/Akt Acts via Glycogen Synthase Kinase 3 To Regulate Recycling of αvβ3 and α5β1 Integrins

Protein kinase B (PKB)/Akt is known to promote cell migration, and this may contribute to the enhanced invasiveness of malignant cells. To elucidate potential mechanisms by which PKB/Akt promotes the migration phenotype, we have investigated its role in the endosomal transport and recycling of integ...

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Autores principales: Roberts, Marnie S., Woods, Alison J., Dale, Trevor C., van der Sluijs, Peter, Norman, Jim C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC344170/
https://ncbi.nlm.nih.gov/pubmed/14749368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.4.1505-1515.2004
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