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Glycogen synthase kinase 3β inhibition enhances Notch1 recycling

The Notch signaling pathway is essential throughout development and remains active into adulthood, where it performs a critical role in tissue homeostasis. The fact that defects in signaling can lead to malignancy illustrates the need to control Notch activity tightly. GSK3β is an established regula...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Zheng, Li, Conner, Sean D.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014177/
https://ncbi.nlm.nih.gov/pubmed/29237816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-07-0474
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