Placental Failure and Impaired Vasculogenesis Result in Embryonic Lethality for Neuropathy Target Esterase-Deficient Mice

Age-dependent neurodegeneration resulting from widespread apoptosis of neurons and glia characterize the Drosophila Swiss Cheese (SWS) mutant. Neuropathy target esterase (NTE), the vertebrate homologue of SWS, reacts with organophosphates which initiate a syndrome of axonal degeneration. NTE is expr...

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Main Authors: Moser, Markus, Li, Yong, Vaupel, Kristina, Kretzschmar, Doris, Kluge, Reinhart, Glynn, Paul, Buettner, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC344166/
https://ncbi.nlm.nih.gov/pubmed/14749382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.4.1667-1679.2004
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