Placental Failure and Impaired Vasculogenesis Result in Embryonic Lethality for Neuropathy Target Esterase-Deficient Mice

Age-dependent neurodegeneration resulting from widespread apoptosis of neurons and glia characterize the Drosophila Swiss Cheese (SWS) mutant. Neuropathy target esterase (NTE), the vertebrate homologue of SWS, reacts with organophosphates which initiate a syndrome of axonal degeneration. NTE is expr...

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Bibliografiske detaljer
Main Authors: Moser, Markus, Li, Yong, Vaupel, Kristina, Kretzschmar, Doris, Kluge, Reinhart, Glynn, Paul, Buettner, Reinhard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC344166/
https://ncbi.nlm.nih.gov/pubmed/14749382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.4.1667-1679.2004
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