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Influence of Tryptophan Contained in 1-Methyl-Tryptophan on Antimicrobial and Immunoregulatory Functions of Indoleamine 2,3-Dioxygenase

Indoleamine 2,3-dioxygenase (IDO) has been identified as an important antimicrobial and immunoregulatory effector molecule essential for the establishment of tolerance by regulating local tryptophan (Trp) concentrations. On the other hand, the immunosuppressive capacity of IDO can have detrimental e...

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Hlavní autoři: Schmidt, Silvia K., Siepmann, Stephan, Kuhlmann, Katja, Meyer, Helmut E., Metzger, Sabine, Pudelko, Sabine, Leineweber, Margret, Däubener, Walter
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441469/
https://ncbi.nlm.nih.gov/pubmed/23028625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044797
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