G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization

The G2019S leucine rich repeat kinase 2 (LRRK2) mutation is the most common genetic cause of Parkinson's disease (PD), clinically and pathologically indistinguishable from idiopathic PD. Mitochondrial abnormalities are a common feature in PD pathogenesis and we have investigated the impact of G...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Papkovskaia, Tatiana D., Chau, Kai-Yin, Inesta-Vaquera, Francisco, Papkovsky, Dmitri B., Healy, Daniel G., Nishio, Koji, Staddon, James, Duchen, Michael R., Hardy, John, Schapira, Anthony H.V., Cooper, J. Mark
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2012
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441120/
https://ncbi.nlm.nih.gov/pubmed/22736029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds244
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