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Reduced effectiveness of escitalopram in the forced swimming test is associated with increased serotonin clearance rate in food restricted rats

Efficacy of antidepressant drugs is often limited. One of the limiting factors may be diet. This study shows that the effect of escitalopram in the forced swimming test is diminished in rats by food restriction that decreased body weight by 8%. The primary target for escitalopram is the serotonin (5...

詳細記述

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書誌詳細
主要な著者: France, CP, Li, J-X, Owens, WA, Koek, W, Toney, GM, Daws, LC
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440869/
https://ncbi.nlm.nih.gov/pubmed/19419596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145709000418
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