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Phosphorylation and microtubule association of the Opitz syndrome protein mid-1 is regulated by protein phosphatase 2A via binding to the regulatory subunit α4

Opitz syndrome (OS) is a human genetic disease characterized by deformities such as cleft palate that are attributable to defects in embryonic development at the midline. Gene mapping has identified OS mutations within a protein called Mid1. Wild-type Mid1 predominantly colocalizes with microtubules...

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Detalhes bibliográficos
Main Authors: Liu, Jun, Prickett, Todd D., Elliott, Elizabeth, Meroni, Germana, Brautigan, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34408/
https://ncbi.nlm.nih.gov/pubmed/11371618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111154698
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