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Expression of DBC1 is associated with nuclear grade and HER2 expression in breast cancer
DBC1/KIAA1967 (deleted in breast cancer 1) is a putative tumor-suppressor gene cloned from breast cancer specimens and is reported to regulate p53-dependent apoptosis through its specific inhibition of SIRT1 deacetylase. Although SIRT1 plays a pivotal role in carcinogenesis by regulating cellular pr...
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| Главные авторы: | , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
D.A. Spandidos
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3440794/ https://ncbi.nlm.nih.gov/pubmed/22977628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2011.333 |
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