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Valproate inhibits colon cancer growth through cell cycle modification in vivo and in vitro
Valproate (VPA) is a well-characterized histone deacetylase inhibitor with anti-neoplastic properties. We analyzed the growth blocking effects and the molecular mode of action of this compound in colorectal cancer cells in vitro and in vivo. Caco-2, SW-480, CX-1 or WIDR cell lines were exposed to VP...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
D.A. Spandidos
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3440661/ https://ncbi.nlm.nih.gov/pubmed/22977502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2011.202 |
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