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Role of PPARγ in COX-2 activation in mycobacterial pulmonary inflammation
Preliminary studies show that intranasal (i.n.) administration of BCG in mice induces M1 activation of alveolar macrophages (MØ) that increase TNF-α production and cyclooxygenase-2 (COX-2) expression but reduce constitutive peroxisome proliferator-activated receptor gamma (PPARγ) expression. However...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3440548/ https://ncbi.nlm.nih.gov/pubmed/22696146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-012-9486-x |
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