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Identifying genetic marker sets associated with phenotypes via an efficient adaptive score test

In recent years, genome-wide association studies (GWAS) and gene-expression profiling have generated a large number of valuable datasets for assessing how genetic variations are related to disease outcomes. With such datasets, it is often of interest to assess the overall effect of a set of genetic...

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Hlavní autoři: Cai, Tianxi, Lin, Xihong, Carroll, Raymond J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440238/
https://ncbi.nlm.nih.gov/pubmed/22734045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxs015
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