Toward Stable Genetic Engineering of Human O-Glycosylation in Plants(1)([C])([W])([OA])

Glycosylation is the most abundant and complex posttranslational modification to be considered for recombinant production of therapeutic proteins. Mucin-type (N-acetylgalactosamine [GalNAc]-type) O-glycosylation is found in eumetazoan cells but absent in plants and yeast, making these cell types an...

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Bibliographic Details
Main Authors: Yang, Zhang, Bennett, Eric P., Jørgensen, Bodil, Drew, Damian P., Arigi, Emma, Mandel, Ulla, Ulvskov, Peter, Levery, Steven B., Clausen, Henrik, Petersen, Bent L.
Format: Artigo
Language:Inglês
Published: American Society of Plant Biologists 2012
Subjects:
Biochemical Processes and Macromolecular Structures
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440218/
https://ncbi.nlm.nih.gov/pubmed/22791304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.112.198200
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