Pharmacokinetics and Postprandial Glycemic Excursions following Insulin Lispro Delivered by Intradermal Microneedle or Subcutaneous Infusion

BACKGROUND: Intradermal (ID) delivery has been shown to accelerate insulin pharmacokinetics (PK). We compared the PK and pharmacodynamic (PD) effects of insulin lispro administered before two daily standardized solid mixed meals (breakfast and lunch), using microneedle-based ID or traditional subcut...

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Détails bibliographiques
Auteurs principaux: McVey, Elaine, Hirsch, Laurence, Sutter, Diane E., Kapitza, Christoph, Dellweg, Sibylle, Clair, Janina, Rebrin, Kerstin, Judge, Kevin, Pettis, Ronald J.
Format: Artigo
Langue:Inglês
Publié: Diabetes Technology Society 2012
Sujets:
Symposium
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440143/
https://ncbi.nlm.nih.gov/pubmed/22920798
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