Particulate Matter, DNA Methylation in Nitric Oxide Synthase, and Childhood Respiratory Disease

Background: Air pollutants have been associated with childhood asthma and wheeze. Epigenetic regulation of nitric oxide synthase—the gene responsible for nitric oxide production—may be affected by air pollutants and contribute to the pathogenesis of asthma and wheeze. Objective: Our goal was to inve...

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Главные авторы: Breton, Carrie V., Salam, Muhammad T., Wang, Xinhui, Byun, Hyang-Min, Siegmund, Kimberly D., Gilliland, Frank D.
Формат: Artigo
Язык:Inglês
Опубликовано: National Institute of Environmental Health Sciences 2012
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Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440108/
https://ncbi.nlm.nih.gov/pubmed/22591701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1104439
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