Interleukin-18 Is an Essential Element in Host Resistance to Experimental Group B Streptococcal Disease in Neonates

Previous studies demonstrated that interleukin-12 (IL-12)-dependent gamma interferon (IFN-γ) responses have a major role in restricting in vivo bacterial growth during infection of mice with group B streptococci (GBS), important human pathogens. Like IL-12, IL-18 is a potent IFN-γ inducer. The role...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Cusumano, Vitaliano, Midiri, Angelina, Valeria Cusumano, Valentina, Bellantoni, Antonella, De Sossi, Giuseppe, Teti, Giuseppe, Beninati, Concetta, Mancuso, Giuseppe
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2004
Subjects:	Host Response and Inflammation
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344002/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14688108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.1.295-300.2004
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