Epitope Mapping of a Monoclonal Antibody Directed against Neisserial Heparin Binding Antigen Using Next Generation Sequencing of Antigen-Specific Libraries.

We explore here the potential of a newly described technology, which is named PROFILER and is based on next generation sequencing of gene-specific lambda phage-displayed libraries, to rapidly and accurately map monoclonal antibody (mAb) epitopes. For this purpose, we used a novel mAb (designated 31E...

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Үндсэн зохиолчид:	Maria Domina, Veronica Lanza Cariccio, Salvatore Benfatto, Mario Venza, Isabella Venza, Danilo Donnarumma, Erika Bartolini, Erica Borgogni, Marco Bruttini, Laura Santini, Angelina Midiri, Roberta Galbo, Letizia Romeo, Francesco Patanè, Carmelo Biondo, Nathalie Norais, Vega Masignani, Giuseppe Teti, Franco Felici, Concetta Beninati
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Public Library of Science (PLoS) 2016-01-01
Цуврал:	PLoS ONE
Онлайн хандалт:	http://europepmc.org/articles/PMC4980009?pdf=render
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!