Zinc Finger Protein Designed to Target 2-Long Terminal Repeat Junctions Interferes with Human Immunodeficiency Virus Integration

Integration of the human immunodeficiency virus type 1 (HIV-1) genome into the host chromosome is a vital step in the HIV life cycle. The highly conserved cytosine–adenine (CA) dinucleotide sequence immediately upstream of the cleavage site is crucial for integrase (IN) activity. As this viral enzym...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sakkhachornphop, Supachai, Barbas, Carlos F., Keawvichit, Rassamee, Wongworapat, Kanlaya, Tayapiwatana, Chatchai
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2012
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440019/
https://ncbi.nlm.nih.gov/pubmed/22429108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.124
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