An integrative probabilistic model for identification of structural variation in sequencing data

Paired-end sequencing is a common approach for identifying structural variation (SV) in genomes. Discrepancies between the observed and expected alignments indicate potential SVs. Most SV detection algorithms use only one of the possible signals and ignore reads with multiple alignments. This result...

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Sonraí Bibleagrafaíochta
Main Authors: Sindi, Suzanne S, Önal, Selim, Peng, Luke C, Wu, Hsin-Ta, Raphael, Benjamin J
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2012
Ábhair:
Method
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439973/
https://ncbi.nlm.nih.gov/pubmed/22452995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-3-r22
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