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Vitamin E prevents NRF2-suppression by allergen in asthmatic alveolar macrophages in vivo

Asthma is a chronic inflammatory airway disease associated with increased generation of reactive oxidant species and disturbed antioxidant defenses. NRF2 is the master transcription factor that regulates the expression of Phase II antioxidant and detoxifying enzymes. Disruption of NRF2 augments oxid...

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Détails bibliographiques
Auteurs principaux: Dworski, Ryszard, Han, Wei, Blackwell, Timothy S., Hoskins, Aimee, Freeman, Michael L.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439844/
https://ncbi.nlm.nih.gov/pubmed/21605660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.04.040
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