A Gene, uge, Is Essential for Klebsiella pneumoniae Virulence

Klebsiella pneumoniae strains typically express both smooth lipopolysaccharide (LPS) with O antigen molecules and capsule polysaccharide (K antigen) on the surface. A single mutation in a gene that codes for a UDP galacturonate 4-epimerase (uge) renders a strain with the O(−):K(−) phenotype (lack of...

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Pubblicato in:	Infect Immun
Autori principali:	Regué, Miguel, Hita, Beatriz, Piqué, Nuria, Izquierdo, Luis, Merino, Susana, Fresno, Sandra, Benedí, Vicente Javier, Tomás, Juan M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Molecular Pathogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343961/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14688080/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.1.54-61.2004
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