A Gene, uge, Is Essential for Klebsiella pneumoniae Virulence

Klebsiella pneumoniae strains typically express both smooth lipopolysaccharide (LPS) with O antigen molecules and capsule polysaccharide (K antigen) on the surface. A single mutation in a gene that codes for a UDP galacturonate 4-epimerase (uge) renders a strain with the O(−):K(−) phenotype (lack of...

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Main Authors: Regué, Miguel, Hita, Beatriz, Piqué, Nuria, Izquierdo, Luis, Merino, Susana, Fresno, Sandra, Benedí, Vicente Javier, Tomás, Juan M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Molecular Pathogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC343961/
https://ncbi.nlm.nih.gov/pubmed/14688080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.1.54-61.2004
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