Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells

Cadmium is a toxic heavy metal which is environmentally and occupationally relevant. The mechanisms underlying cadmium-induced autophagy are not yet completely understood. The present study shows that cadmium induces autophagy, as demonstrated by the increase of LC3-II formation and the GFP-LC3 punc...

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Detalhes bibliográficos
Main Authors: Son, Young-Ok, Wang, Xin, Hitron, John Andrew, Zhang, Zhuo, Cheng, Senping, Budhraja, Amit, Ding, Songze, Lee, Jeong-Chae, Shi, Xianglin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439510/
https://ncbi.nlm.nih.gov/pubmed/21767558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2011.06.024
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