Sirtuin 1 Regulates SREBP-1c Expression in a LXR-Dependent Manner in Skeletal Muscle

Sirtuin 1 (SIRT1), a NAD(+)-dependent protein deacetylase, has emerged as a main determinant of whole body homeostasis in mammals by regulating a large spectrum of transcriptional regulators in metabolically relevant tissue such as liver, adipose tissue and skeletal muscle. Sterol regulatory element...

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Autors principals: Defour, Aurélia, Dessalle, Kevin, Castro Perez, Andréa, Poyot, Thomas, Castells, Josiane, Gallot, Yann Simon, Durand, Christine, Euthine, Vanessa, Gu, Yansong, Béchet, Daniel, Peinnequin, André, Lefai, Etienne, Freyssenet, Damien
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439460/
https://ncbi.nlm.nih.gov/pubmed/22984430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043490
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