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Bidirectional Activity of the NWC Promoter Is Responsible for RAG-2 Transcription in Non-Lymphoid Cells

The recombination-activating genes (RAG-1 and RAG-2) encode a V(D)J recombinase responsible for rearrangements of antigen-receptor genes during T and B cell development, and RAG expression is known to correlate strictly with the process of rearrangement. In contrast to RAG-1, the expression of RAG-2...

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Detalhes bibliográficos
Main Authors: Laszkiewicz, Agnieszka, Sniezewski, Lukasz, Kasztura, Monika, Bzdzion, Lukasz, Cebrat, Malgorzata, Kisielow, Pawel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439442/
https://ncbi.nlm.nih.gov/pubmed/22984564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044807
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