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Norcantharidin Facilitates LPS-Mediated Immune Responses by Up-Regulation of AKT/NF-κB Signaling in Macrophages

Norcantharidin (NCTD), a demethylated analog of cantharidin, is a common used clinical drug to inhibit proliferation and metastasis of cancer cells. But the role of NCTD in modulating immune responses remains unknown. Here, we investigated the function and mechanism of NCTD in regulation of TLR4 ass...

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Autori principali: Zhao, Qufei, Qian, Yu, Li, Ruimei, Tan, Binghe, Han, Honghui, Liu, Mingyao, Qian, Min, Du, Bing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439369/
https://ncbi.nlm.nih.gov/pubmed/22984593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044956
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