Norcantharidin Facilitates LPS-Mediated Immune Responses by Up-Regulation of AKT/NF-κB Signaling in Macrophages

Norcantharidin (NCTD), a demethylated analog of cantharidin, is a common used clinical drug to inhibit proliferation and metastasis of cancer cells. But the role of NCTD in modulating immune responses remains unknown. Here, we investigated the function and mechanism of NCTD in regulation of TLR4 ass...

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Detalhes bibliográficos
Main Authors: Zhao, Qufei, Qian, Yu, Li, Ruimei, Tan, Binghe, Han, Honghui, Liu, Mingyao, Qian, Min, Du, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439369/
https://ncbi.nlm.nih.gov/pubmed/22984593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044956
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