The promoter methylation and expression of the O6-methylguanine-DNA methyltransferase gene in uterine sarcoma and carcinosarcoma

O6-methylguanine-DNA methyltransferase (MGMT) gene promoter hypermethylation is observed in a number of solid tumors and is correlated with the silencing of MGMT expression. In glioblastoma patients treated with the alkylating agent temozolomide, MGMT gene methylation status was shown to have predic...

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Bibliografski detalji
Glavni autori: BUJKO, MATEUSZ, KOWALEWSKA, MAGDALENA, DANSKA-BIDZINSKA, ANNA, BAKULA-ZALEWSKA, ELWIRA, SIEDECKI, JANUSZ A., BIDZINSKI, MARIUSZ
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2012
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439109/
https://ncbi.nlm.nih.gov/pubmed/22970054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2012.771
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