Deciphering the Role of CD1e Protein in Mycobacterial Phosphatidyl-myo-inositol Mannosides (PIM) Processing for Presentation by CD1b to T Lymphocytes

Lipids are important antigens that induce T cell-mediated specific immune responses. They are presented to T lymphocytes by a specific class of MHC-I like proteins, termed CD1. The majority of the described CD1-presented mycobacterial antigens are presented by the CD1b isoform. We previously demonst...

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Main Authors: Cala-De Paepe, Diane, Layre, Emilie, Giacometti, Gaëlle, Garcia-Alles, Luis F., Mori, Lucia, Hanau, Daniel, de Libero, Gennaro, de la Salle, Henri, Puzo, Germain, Gilleron, Martine
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Lipids
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438982/
https://ncbi.nlm.nih.gov/pubmed/22782895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.386300
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