Specialized Hsp70 Chaperone (HscA) Binds Preferentially to the Disordered Form, whereas J-protein (HscB) Binds Preferentially to the Structured Form of the Iron-Sulfur Cluster Scaffold Protein (IscU)

The Escherichia coli protein IscU serves as the scaffold for Fe-S cluster assembly and the vehicle for Fe-S cluster transfer to acceptor proteins, such as apoferredoxin. IscU populates two conformational states in solution, a structured conformation (S) that resembles the conformation of the holopro...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Jin Hae, Tonelli, Marco, Frederick, Ronnie O., Chow, Darius C.-F., Markley, John L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438969/
https://ncbi.nlm.nih.gov/pubmed/22782893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.352617
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