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Endoplasmic Reticulum Stress Induces a Caspase-dependent N-terminal Cleavage of RBX1 Protein in B Cells

Endoplasmic reticulum (ER) stress develops when the ER is overloaded with too many proteins to fold. This elicits a signaling pathway called the unfolded protein response. The unfolded protein response is physiologically required for the terminal development of B cells into antibody-secreting plasma...

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Autors principals: Shteingart, Shimon, Hadar, Rivka, Cohen, Itamar, Ravid, Tommer, Tirosh, Boaz
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438954/
https://ncbi.nlm.nih.gov/pubmed/22822056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.314583
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