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MicroRNA-30d Induces Insulin Transcription Factor MafA and Insulin Production by Targeting Mitogen-activated Protein 4 Kinase 4 (MAP4K4) in Pancreatic β-Cells

MicroRNAs (miRNAs) represent small noncoding RNAs that play a role in many diseases, including diabetes. miRNAs target genes important for pancreas development, β-cell proliferation, insulin secretion, and exocytosis. Previously, we documented that microRNA-30d (miR-30d), one of miRNAs up-regulated...

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מידע ביבליוגרפי
Main Authors: Zhao, Xiaomin, Mohan, Ramkumar, Özcan, Sabire, Tang, Xiaoqing
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438947/
https://ncbi.nlm.nih.gov/pubmed/22733810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362632
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