Bayesian Methods for Multivariate Modeling of Pleiotropic SNP Associations and Genetic Risk Prediction

Genome-wide association studies (GWAS) have identified numerous associations between genetic loci and individual phenotypes; however, relatively few GWAS have attempted to detect pleiotropic associations, in which loci are simultaneously associated with multiple distinct phenotypes. We show that ple...

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Hauptverfasser: Hartley, Stephen W., Monti, Stefano, Liu, Ching-Ti, Steinberg, Martin H., Sebastiani, Paola
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Research Foundation 2012
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438684/
https://ncbi.nlm.nih.gov/pubmed/22973300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00176
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