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Braf and erbB2 mutations correlate with smoking status in lung cancer patients

The erbB pathway involves a family of tyrosine kinases and contributes to resistance or sensitivity to chemotherapy in many tumor types. Somatic mutations of the epidermal growth factor receptor (EGFR) gene at the kinase domain have been found in lung cancer patients. These mutations are correlated...

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Dettagli Bibliografici
Autori principali: SASAKI, HIDEFUMI, SHITARA, MASAYUKI, YOKOTA, KEISUKE, OKUDA, KATSUHIRO, HIKOSAKA, YU, MORIYAMA, SATORU, YANO, MOTOKI, FUJII, YOSHITAKA
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438531/
https://ncbi.nlm.nih.gov/pubmed/22969966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2012.500
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