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RagD gene expression and NRF2 mutations in lung squamous cell carcinomas

RagD is a member of the small G protein family, which encodes a recently discovered activator of the mTOR pathway. In vitro, RagD plays an important role in the proliferation of NRF2 gene (NFE2L2) mutated cancer cells. We hypothesized that tumor RagD expression may be correlated with the mutation st...

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Dettagli Bibliografici
Autori principali: SASAKI, HIDEFUMI, SHITARA, MASAYUKI, YOKOTA, KEISUKE, HIKOSAKA, YU, MORIYAMA, SATORU, YANO, MOTOKI, FUJII, YOSHITAKA
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506764/
https://ncbi.nlm.nih.gov/pubmed/23226795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2012.938
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