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Using Enhanced Sampling and Structural Restraints to Refine Atomic Structures into Low-resolution Electron Microscopy Maps

For a variety of problems in structural biology, low-resolution maps generated by electron microscopy (EM) imaging are often interpreted with the help of various flexible-fitting computational algorithms. In this work, we systematically analyze the quality of final models of various proteins obtaine...

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Detalhes bibliográficos
Main Authors: Vashisth, Harish, Skiniotis, Georgios, Brooks, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438525/
https://ncbi.nlm.nih.gov/pubmed/22958641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.08.007
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