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Molecular identification of GD3 as a suppressor of the innate immune response in ovarian cancer

Tumors often display mechanisms to avoid or suppress immune recognition. One such mechanism is the shedding of gangliosides into the local tumor microenvironment, and a high concentration of circulating gangliosides is associated with poor prognosis. In this study, we identify ganglioside GD3, which...

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Détails bibliographiques
Auteurs principaux: Webb, Tonya J., Li, Xiangming, Giuntoli, Robert L., Lopez, Pablo H.H., Heuser, Christoph, Schnaar, Ronald L., Tsuji, Moriya, Kurts, Christian, Oelke, Mathias, Schneck, Jonathan P.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438513/
https://ncbi.nlm.nih.gov/pubmed/22649190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2695
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