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Molecular identification of GD3 as a suppressor of the innate immune response in ovarian cancer

Tumors often display mechanisms to avoid or suppress immune recognition. One such mechanism is the shedding of gangliosides into the local tumor microenvironment, and a high concentration of circulating gangliosides is associated with poor prognosis. In this study, we identify ganglioside GD3, which...

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Detalhes bibliográficos
Main Authors: Webb, Tonya J., Li, Xiangming, Giuntoli, Robert L., Lopez, Pablo H.H., Heuser, Christoph, Schnaar, Ronald L., Tsuji, Moriya, Kurts, Christian, Oelke, Mathias, Schneck, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438513/
https://ncbi.nlm.nih.gov/pubmed/22649190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2695
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