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The emergence and maintenance of sickle cell hotspots in the Mediterranean

Genetic disorders of haemoglobin (haemoglobinopathies), including the thalassaemias and sickle cell anaemia, abound in historically malarious regions, due to the protection they provide against death from severe malaria. Despite the overall spatial correlation between malaria and these disorders, in...

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Autores principales: Penman, Bridget S., Gupta, Sunetra, Buckee, Caroline O.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438445/
https://ncbi.nlm.nih.gov/pubmed/22704979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2012.06.001
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