Genetic variation that predicts platinum sensitivity reveals the role of miR-193b* in chemotherapeutic susceptibility

Platinum agents are the backbone of cancer chemotherapy. Recently we identified and replicated the role of a single nucleotide polymorphism (SNP, rs1649942) in predicting platinum sensitivity both in vitro and in vivo. Using the CEU samples from the International HapMap Project, we found the same SN...

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Bibliographic Details
Main Authors:	Ziliak, Dana, Gamazon, Eric R., LaCroix, Bonnie, Im, Hae Kyung, Wen, Yujia, Huang, Rong Stephanie
Format:	Artigo
Language:	Inglês
Published:	2012
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3438340/ https://ncbi.nlm.nih.gov/pubmed/22752226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0221
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Genetic variation that predicts platinum sensitivity reveals the role of miR-193b* in chemotherapeutic susceptibility

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